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JAMA Netw Open

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Flu vaccines retained benefit during drifted H3N2 season

The 2025-2026 season caused substantial illness, but vaccines and antivirals remained effective. . .

JAMA Health Forum

Medicare drug caps tied to more use of expensive meds

Use of the most expensive medications rose after the cap took effect, while fills of low- and mid-priced drugs barely changed. . .

Am J Hum Genet

Social factors rival genes in predicting common diseases

Adding social and behavioral context to risk models improved prediction for all six diseases studied, and outweighed genetic risk scores for most of them. . .

JAMA Netw Open

Maternal heart health may shape child development

Japanese cohort study links poorer cardiovascular health during pregnancy with higher risk of developmental delay at age 4. . .

Circulation

Childhood sugary drinks, juice associated with adult hypertension

Higher intake of sweetened beverages and fruit juice predicted greater adult risk over 25 years. . .

epocrates

Survey: Clinicians want clearer evidence behind guidelines

Uncertainty rises when recommendations change, while confidence drops when major health organizations disagree. . .

JAMA Pediatr

GLP-1s work best in teens with lifestyle support

A pooled analysis of 42 pediatric trials found that combining obesity medication with lifestyle treatment was tied to the largest BMI reductions, while structured lifestyle treatment alone still beat every drug used on its own. . .

Cancer

New clues emerge in early-onset colon cancer risk

Sex, ethnicity, and early-life characteristics tracked with early-onset colon cancer risk in a California birth-cohort study, pointing to origins that may begin before birth. . .

Ann Intern Med

Antibiotics still routine for uncomplicated diverticulitis despite guideline shift

VA data show outpatient prescribing for uncomplicated diverticulitis remains above 95%. . .

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